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STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID

STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID

The aim of this study is to present a novel synthesis technique and investigate the properties of nanoscale calcium carbonate samples stabilized with hyaluronic acid, a biopolymer. The samples were produced through chemical precipitation in an aqueous environment, utilizing calcium acetate as a calc...

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Главные авторы: Blinov, A. V., Блинов, А. В., Rekhman, Z. A., Рехман, З. А., Askerova, A. S., Аскерова, А. С., Pirogov, M. A., Пирогов, М. А., Yasnaya, M. A., Ясная, М. А., Selimov, M. A., Селимов, М. А., Prasolova, A. V., Прасолова, А. В.
Формат: Статья
Язык:Russian
Опубликовано: Bauman Press 2025
Темы:
Biopolymers
Osteotropic micronutrients
Calcium carbonate nanoparticles
Hyaluronic acid
Online-ссылка:https://dspace.ncfu.ru/handle/123456789/29790
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spelling ir-123456789-297902025-02-20T09:24:17Z STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID ИССЛЕДОВАНИЕ СВОЙСTВ НАНОPАЗМЕPНОГО КАPБОНАTА КАЛЬЦИЯ, СTАБИЛИЗИPОВАННОГО ГИАЛУPОНОВОЙ КИСЛОTОЙ Blinov, A. V. Блинов, А. В. Rekhman, Z. A. Рехман, З. А. Askerova, A. S. Аскерова, А. С. Pirogov, M. A. Пирогов, М. А. Yasnaya, M. A. Ясная, М. А. Selimov, M. A. Селимов, М. А. Prasolova, A. V. Прасолова, А. В. Biopolymers Osteotropic micronutrients Calcium carbonate nanoparticles Hyaluronic acid The aim of this study is to present a novel synthesis technique and investigate the properties of nanoscale calcium carbonate samples stabilized with hyaluronic acid, a biopolymer. The samples were produced through chemical precipitation in an aqueous environment, utilizing calcium acetate as a calcium-containing precursor, hyaluronic acid as a stabilizing agent, and ammonium carbonate as a precipitating agent. A sample of nanosized calcium carbonate, modified with the biopolymer, was analyzed using dynamic light scattering, acoustic, and electroacoustic spectroscopies, scanning electron microscopy, X-ray diffraction, and computational quantum chemical modeling techniques. The results obtained from photon correlation spectroscopy analysis indicated that the sample had a hydrodynamic radius less than 30 nanometers and an electrophoretic mobility close to zero. Investigation of the phase composition revealed that the sample consisted of a single phase with a rhombohedral crystalline structure. Based on the analysis of the microstructural features of nanoscale calcium carbonate stabilized with hyaluronic acid, it was found that the sample consists of cubic particles with dimensions ranging from 0.3 to 5 microns. These particles are composed of smaller nanoparticles. Quantum chemical modeling was used to determine the optimal molecular structure of the complex formed between calcium carbonate nanoparticles and hyaluronic acid. The modeling also allowed us to calculate the quantum characteristics of this complex 2025-02-20T09:22:18Z 2025-02-20T09:22:18Z 2024 Статья Blinov A.V., Rekhman Z.A., Askerova A.S., Pirogov M.A., Yasnaya M.A., Selimov M.A., Prasolova A.V. STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID // Herald of the Bauman Moscow State Technical University, Series Natural Sciences. - 2024. - 117 (6). - pp. 72 - 87. https://dspace.ncfu.ru/handle/123456789/29790 ru Herald of the Bauman Moscow State Technical University, Series Natural Sciences application/pdf Bauman Press
institution СКФУ
collection Репозиторий
language Russian
topic Biopolymers
Osteotropic micronutrients
Calcium carbonate nanoparticles
Hyaluronic acid
spellingShingle Biopolymers
Osteotropic micronutrients
Calcium carbonate nanoparticles
Hyaluronic acid
Blinov, A. V.
Блинов, А. В.
Rekhman, Z. A.
Рехман, З. А.
Askerova, A. S.
Аскерова, А. С.
Pirogov, M. A.
Пирогов, М. А.
Yasnaya, M. A.
Ясная, М. А.
Selimov, M. A.
Селимов, М. А.
Prasolova, A. V.
Прасолова, А. В.
STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID
description The aim of this study is to present a novel synthesis technique and investigate the properties of nanoscale calcium carbonate samples stabilized with hyaluronic acid, a biopolymer. The samples were produced through chemical precipitation in an aqueous environment, utilizing calcium acetate as a calcium-containing precursor, hyaluronic acid as a stabilizing agent, and ammonium carbonate as a precipitating agent. A sample of nanosized calcium carbonate, modified with the biopolymer, was analyzed using dynamic light scattering, acoustic, and electroacoustic spectroscopies, scanning electron microscopy, X-ray diffraction, and computational quantum chemical modeling techniques. The results obtained from photon correlation spectroscopy analysis indicated that the sample had a hydrodynamic radius less than 30 nanometers and an electrophoretic mobility close to zero. Investigation of the phase composition revealed that the sample consisted of a single phase with a rhombohedral crystalline structure. Based on the analysis of the microstructural features of nanoscale calcium carbonate stabilized with hyaluronic acid, it was found that the sample consists of cubic particles with dimensions ranging from 0.3 to 5 microns. These particles are composed of smaller nanoparticles. Quantum chemical modeling was used to determine the optimal molecular structure of the complex formed between calcium carbonate nanoparticles and hyaluronic acid. The modeling also allowed us to calculate the quantum characteristics of this complex
format Статья
author Blinov, A. V.
Блинов, А. В.
Rekhman, Z. A.
Рехман, З. А.
Askerova, A. S.
Аскерова, А. С.
Pirogov, M. A.
Пирогов, М. А.
Yasnaya, M. A.
Ясная, М. А.
Selimov, M. A.
Селимов, М. А.
Prasolova, A. V.
Прасолова, А. В.
author_facet Blinov, A. V.
Блинов, А. В.
Rekhman, Z. A.
Рехман, З. А.
Askerova, A. S.
Аскерова, А. С.
Pirogov, M. A.
Пирогов, М. А.
Yasnaya, M. A.
Ясная, М. А.
Selimov, M. A.
Селимов, М. А.
Prasolova, A. V.
Прасолова, А. В.
author_sort Blinov, A. V.
title STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID
title_short STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID
title_full STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID
title_fullStr STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID
title_full_unstemmed STUDY OF THE PROPERTIES OF NANOSCALE CALCIUM CARBONATE STABILIZED WITH HYALURONIC ACID
title_sort study of the properties of nanoscale calcium carbonate stabilized with hyaluronic acid
publisher Bauman Press
publishDate 2025
url https://dspace.ncfu.ru/handle/123456789/29790
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