One-pot synthesis of 4-methyl-2-alkyl quinazoline-N-oxides by cascade acetamidation–acylation of simple electron-rich arenes with primary nitroalkanes
A one-pot, two-stage reaction sequence leading to 2,4-dialkylquinazoline-3-oxide derivatives has been developed. It begins with the in situ formation of anilides by the Beckmann-type acetamidation of simple, bearing electron-donating groups arenes with primary nitroalkanes in polyphosphoric acid. Su...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Статья |
| Sprache: | English |
| Veröffentlicht: |
Elsevier Ltd
2025
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| Schlagworte: | |
| Online Zugang: | https://dspace.ncfu.ru/handle/123456789/30390 |
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