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One-pot synthesis of substituted quinolines and 3,3′-(arylmethylene)bis(1H-indoles) via a metal-free polyphosphoric acid-mediated acetylene hydrolysis strategy

One-pot synthesis of substituted quinolines and 3,3′-(arylmethylene)bis(1H-indoles) via a metal-free polyphosphoric acid-mediated acetylene hydrolysis strategy

Simple one-pot methods for the synthesis of polysubstituted quinolines and 3,3 ′-(arylmethylene) bis (1H-indoles) have been developed using a polyphosphoric acid-mediated alkynes hydrolysis strategy. Sequential addition of substituted alkynes to an o-nitro(o-aminophenyl)carbonyl compound under solve...

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Main Authors: Arutiunov, N. A., Арутюнов, Н. А., Makieva, D. C., Макиева, Д. С., Zatsepilina, A. M., Зацепилина, А. М., Aksenova, I. V., Аксенова, И. В., Tolstov, K. V., Толстов, К. В., Shtal, D. A., Шталь, Д. А., Korneeva, A. A., Корнеева, А. А., Aleksandrova, E. V., Александрова, Е. В., Aksenov, A. V., Аксенов, А. В.
Format: Статья
Language:English
Published: Elsevier Ltd 2025
Subjects:
Acetylenes
Three-component reaction
Heterocyclic compounds
Hydrolysis
Indoles
Intramolecular cyclization
Nucleophilic addition
Polyphosphoric acid
Propargyl alcohol
Quinolines
Online Access:https://dspace.ncfu.ru/handle/123456789/31111
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https://dspace.ncfu.ru/handle/123456789/31111

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