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Synthesis of 2,4-Disubstituted Quinolines by the Reaction of Propargylic Alcohols with Anilines in a Polyphosphoric Acid Medium

Synthesis of 2,4-Disubstituted Quinolines by the Reaction of Propargylic Alcohols with Anilines in a Polyphosphoric Acid Medium

A novel method for quinoline synthesis based on the interaction of propargylic alcohols with anilines in the presence of polyphosphoric acid (PPA) has been developed. It has been discovered that propargylic alcohols in a PPA medium are capable of hydrolyzing into chalcones. The use of PPA in ethyl a...

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Главные авторы: Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Akulova, A. S., Акулова, А. С., Makieva, D. C., Макиева, Д. С., Aksenova, I. V., Аксенова, И. В., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, D. A., Аксенов, Д. А.
Formato: Статья
Idioma:English
Publicado em: Pleiades Publishing 2025
Assuntos:
Acetylenes
The Friedel-crafts reaction
Heterocyclization
Kucherov reaction
Propargyl alcohols
Quinolines
Acesso em linha:https://dspace.ncfu.ru/handle/123456789/31842
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