Перейти до змісту

Synthesis of 2,4-Disubstituted Quinolines by the Reaction of Propargylic Alcohols with Anilines in a Polyphosphoric Acid Medium

A novel method for quinoline synthesis based on the interaction of propargylic alcohols with anilines in the presence of polyphosphoric acid (PPA) has been developed. It has been discovered that propargylic alcohols in a PPA medium are capable of hydrolyzing into chalcones. The use of PPA in ethyl a...

Повний опис

Збережено в:
Бібліографічні деталі
Автори: Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Akulova, A. S., Акулова, А. С., Makieva, D. C., Макиева, Д. С., Aksenova, I. V., Аксенова, И. В., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, D. A., Аксенов, Д. А.
Формат: Статья
Мова:English
Опубліковано: Pleiades Publishing 2025
Предмети:
Онлайн доступ:https://dspace.ncfu.ru/handle/123456789/31842
Теги: Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!
Опис
Резюме:A novel method for quinoline synthesis based on the interaction of propargylic alcohols with anilines in the presence of polyphosphoric acid (PPA) has been developed. It has been discovered that propargylic alcohols in a PPA medium are capable of hydrolyzing into chalcones. The use of PPA in ethyl acetate solution has been demonstrated for the first time.