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Synthesis of 2,4-Disubstituted Quinolines by the Reaction of Propargylic Alcohols with Anilines in a Polyphosphoric Acid Medium

Synthesis of 2,4-Disubstituted Quinolines by the Reaction of Propargylic Alcohols with Anilines in a Polyphosphoric Acid Medium

A novel method for quinoline synthesis based on the interaction of propargylic alcohols with anilines in the presence of polyphosphoric acid (PPA) has been developed. It has been discovered that propargylic alcohols in a PPA medium are capable of hydrolyzing into chalcones. The use of PPA in ethyl a...

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Autors principals: Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Akulova, A. S., Акулова, А. С., Makieva, D. C., Макиева, Д. С., Aksenova, I. V., Аксенова, И. В., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, D. A., Аксенов, Д. А.
Format: Статья
Idioma:English
Publicat: Pleiades Publishing 2025
Matèries:
Acetylenes
The Friedel-crafts reaction
Heterocyclization
Kucherov reaction
Propargyl alcohols
Quinolines
Accés en línia:https://dspace.ncfu.ru/handle/123456789/31842
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