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Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity

Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity

We discovered a reaction of nitroalkanes with 2-hydrazinylquinolines, 2-hydrazinylpyridines and bis-2,4-dihydrazinylpyrimidines in polyphosphoric acid (PPA) affording 1,2,4-triazolo[4,3-a]quinolines, 1,2,4-triazolo[4,3-a]pyridines and bis[1,2,4]triazolo[4,3-a:4',3'-c]pyrimidines, respectiv...

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Bibliographic Details
Main Authors: Aksenov, N. A., Аксенов, Н. А., Aksenov, A. V., Аксенов, А. В., Kirilov, N. K., Кирилов, Н. К., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, D. A., Аксенов, Д. А., Rubin, M. A., Рубин, М. А.
Format: Статья
Language:English
Published: NLM (Medline) 2020
Subjects:
Neuroblastoma
Nitroalkanes
Synthesis of triazole-fused heterocycles
Neuroblastoma therapy
Online Access:https://dspace.ncfu.ru/handle/20.500.12258/13876
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https://dspace.ncfu.ru/handle/20.500.12258/13876

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