Spirocyclic thienopyrimidines: synthesis, new rearrangement under vilsmeier conditions and in silico prediction of anticancer activity
Aim. To find novel anticancer lead molecules among easily available spiro-fused thieno[2,3-d] pyrimidines. Methods. Organic synthesis, spectral methods and molecular docking. Results. New spiro heterocycles were synthesized by condensation of 2-aminothiophene-3-carbonitriles with cyclic ketones via...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Статья |
| Sprache: | English |
| Veröffentlicht: |
National Academy of Sciences of Ukraine
2020
|
| Schlagworte: | |
| Online Zugang: | https://dspace.ncfu.ru/handle/20.500.12258/14298 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|