Spirocyclic thienopyrimidines: synthesis, new rearrangement under vilsmeier conditions and in silico prediction of anticancer activity
Aim. To find novel anticancer lead molecules among easily available spiro-fused thieno[2,3-d] pyrimidines. Methods. Organic synthesis, spectral methods and molecular docking. Results. New spiro heterocycles were synthesized by condensation of 2-aminothiophene-3-carbonitriles with cyclic ketones via...
Salvato in:
Autori principali: | , |
---|---|
Natura: | Статья |
Lingua: | English |
Pubblicazione: |
National Academy of Sciences of Ukraine
2020
|
Soggetti: | |
Accesso online: | https://dspace.ncfu.ru/handle/20.500.12258/14298 |
Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|