Spirocyclic thienopyrimidines: synthesis, new rearrangement under vilsmeier conditions and in silico prediction of anticancer activity
Aim. To find novel anticancer lead molecules among easily available spiro-fused thieno[2,3-d] pyrimidines. Methods. Organic synthesis, spectral methods and molecular docking. Results. New spiro heterocycles were synthesized by condensation of 2-aminothiophene-3-carbonitriles with cyclic ketones via...
Сохранить в:
| Главные авторы: | , |
|---|---|
| 格式: | Статья |
| 語言: | English |
| 出版: |
National Academy of Sciences of Ukraine
2020
|
| 主題: | |
| 在線閱讀: | https://dspace.ncfu.ru/handle/20.500.12258/14298 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|