Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence
A highly efficient one-pot procedure combining conjugate addition of Grignard reagents to (2-nitroalkenyl)indoles and sub-sequent Brønsted acid-assisted spirocyclization allowed for preparation of 4′H-spiro[indole-3,5′-isoxazoles] in a diastereomerically selective fashion. Utilization of alkyl Grign...
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| Format: | Статья |
| Sprache: | English |
| Veröffentlicht: |
Royal Society of Chemistry
2021
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| Schlagworte: | |
| Online Zugang: | https://dspace.ncfu.ru/handle/20.500.12258/14853 |
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