Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence
A highly efficient one-pot procedure combining conjugate addition of Grignard reagents to (2-nitroalkenyl)indoles and sub-sequent Brønsted acid-assisted spirocyclization allowed for preparation of 4′H-spiro[indole-3,5′-isoxazoles] in a diastereomerically selective fashion. Utilization of alkyl Grign...
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| Главные авторы: | , , , , , , , , , , , |
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| Formato: | Статья |
| Idioma: | English |
| Publicado: |
Royal Society of Chemistry
2021
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| Темы: | |
| Acceso en liña: | https://dspace.ncfu.ru/handle/20.500.12258/14853 |
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