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Synthesis of 1,5-diazocin-2-ones

This review is focused on the synthetic approaches to the eight-membered nitrogen heterocycles, 1,5-diazocin-2-ones, exhibiting promising biological activities. Nomenclature of these compounds is considered and the examples of the natural and pharmacologically important compounds of the 1,5-diazocin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aksenov, A. V., Аксенов, А. В., Rubin, M. A., Рубин, М. А.
Format: Статья
Sprache:English
Veröffentlicht: Springer 2021
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Online Zugang:https://dspace.ncfu.ru/handle/20.500.12258/17719
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Beschreibung
Zusammenfassung:This review is focused on the synthetic approaches to the eight-membered nitrogen heterocycles, 1,5-diazocin-2-ones, exhibiting promising biological activities. Nomenclature of these compounds is considered and the examples of the natural and pharmacologically important compounds of the 1,5-diazocin-2-one family are given. Synthetic approaches towards these compounds in accordance with groups and classes of reactions, as well as cascade transformations were systematically analyzed. The review contains 63 references, covering the period from 1955 to early 2021