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Synthesis of 1,5-diazocin-2-ones

This review is focused on the synthetic approaches to the eight-membered nitrogen heterocycles, 1,5-diazocin-2-ones, exhibiting promising biological activities. Nomenclature of these compounds is considered and the examples of the natural and pharmacologically important compounds of the 1,5-diazocin...

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Detalhes bibliográficos
Principais autores: Aksenov, A. V., Аксенов, А. В., Rubin, M. A., Рубин, М. А.
Formato: Статья
Idioma:English
Publicado em: Springer 2021
Assuntos:
Acesso em linha:https://dspace.ncfu.ru/handle/20.500.12258/17719
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Descrição
Resumo:This review is focused on the synthetic approaches to the eight-membered nitrogen heterocycles, 1,5-diazocin-2-ones, exhibiting promising biological activities. Nomenclature of these compounds is considered and the examples of the natural and pharmacologically important compounds of the 1,5-diazocin-2-one family are given. Synthetic approaches towards these compounds in accordance with groups and classes of reactions, as well as cascade transformations were systematically analyzed. The review contains 63 references, covering the period from 1955 to early 2021