Synthesis of 1,5-diazocin-2-ones

Synthesis of 1,5-diazocin-2-ones

This review is focused on the synthetic approaches to the eight-membered nitrogen heterocycles, 1,5-diazocin-2-ones, exhibiting promising biological activities. Nomenclature of these compounds is considered and the examples of the natural and pharmacologically important compounds of the 1,5-diazocin...

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Bibliografiske detaljer
Главные авторы:	Aksenov, A. V., Аксенов, А. В., Rubin, M. A., Рубин, М. А.
Format:	Статья
Sprog:	English
Udgivet:	Springer 2021
Fag:	Zeta-azalactams Biological activity 1,5-diazocin-2-ones Synthesis
Online adgang:	https://dspace.ncfu.ru/handle/20.500.12258/17719
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Lignende værker

Synthesis and some properties of new 5-Hydroxy-2-[(hetarylthio)methyl]-4H-pyran-4-ones
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New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents
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Nitroalkenes as surrogates for cyanomethylium species in a one-pot synthesis of non-symmetric diarylacetonitriles
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Udgivet: (2018)

New methods of synthesis, structure and aminomethylation of 4-imino-2-(dicyanomethylene)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile
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Udgivet: (2021)

One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
af: Rubin, M. A., и др.
Udgivet: (2018)

Novel convenient one-pot method for the synthesis of indoloquinolines
af: Aksenov, N. A., и др.
Udgivet: (2019)

Synthesis and Aminomethylation of 2-Amino-4-(2-chlorophenyl)-6-(dicyanomethyl)-1,4-dihydropyridine-3,5-dicarbonitrile N-Methylmorpholinium Salt
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Udgivet: (2022)

7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity
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Udgivet: (2022)

Synthesis and properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
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Udgivet: (2019)

Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes
af: Aksenov, D. A., и др.
Udgivet: (2020)

SNH-Arylamination of 1-methylquinolin-2(1H)-one Nitro Derivatives
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Udgivet: (2021)

N-substituted 1H-pyrimidin-4-one derivatives possessing anxiolytic activity
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7-(2-Aryl-1-cyanovinyl)-1,2,3,4-tetrahydropyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles: Synthesis and Biological Activity
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Udgivet: (2023)

Efficient one-pot synthesis of 1-arylcycloprop-2-ene-1-carboxamides
af: Rubin, M. A., и др.
Udgivet: (2018)

One-pot synthesis of benzoxazoles via the metal-free ortho-C-H functionalization of phenols with nitroalkanes
af: Aksenov, N. A., и др.
Udgivet: (2018)

A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
af: Aksenov, A. V., и др.
Udgivet: (2018)

A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
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Udgivet: (2018)

Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives
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Udgivet: (2021)

1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction
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Udgivet: (2021)

Synthesis and Structure of 4-Aryl-3,6-dioxo-2,3,4,5,6,7-hexahydroisothiazolo[5,4-b]pyridine-5-carbonitriles
af: Dotsenko, V. V., и др.
Udgivet: (2023)

Dihydro-2: H -thiopyran-3(4 H)-one-1,1-dioxide-a versatile building block for the synthesis of new thiopyran-based heterocyclic systems
af: Dotsenko, V. V., и др.
Udgivet: (2018)

A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams
af: Aksenov, A. V., и др.
Udgivet: (2023)

One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
af: Aksenov, A. V., и др.
Udgivet: (2018)

One-pot, three-component assembly of indoloquinolines: total synthesis of isocryptolepine
af: Aksenov, A. V., и др.
Udgivet: (2018)

Electrochemical Oxidation of 3-Aryl-2-cyanothioacrylamides
af: Dotsenko, V. V., и др.
Udgivet: (2023)

Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
af: Dotsenko, V. V., и др.
Udgivet: (2021)

Synthesis and Structure of (2E)-3-Aryl(hetaryl)-2-[5-bromo-4-aryl(hetaryl)-1,3-thiazol-2-yl]acrylonitriles
af: Dotsenko, V. V., и др.
Udgivet: (2021)

New Heterocyclization Reactions with Malononitrile Dimer
af: Dotsenko, V. V., и др.
Udgivet: (2024)

Rational design of an efficient one-pot synthesis of 6H-pyrrolo[2,3,4- gh] perimidines in polyphosphoric acid
af: Aksenov, A. V., и др.
Udgivet: (2018)

[3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor
af: Aksenov, A. V., и др.
Udgivet: (2021)

Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
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Udgivet: (2019)

A sequence of acylamination and acylation reactions in polyphosphoric acid – a novel approach to the Friedländer synthesis of 2-arylquinolines
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New Azepine-Furan Spirocyclic Structures in the Reaction of 4-Aroyl-1,2-dihydrobenzo[d]azepines and 2-Aroyl-4,5-dihydrophenanthreno[1,2-d]azepine with Formaldehyde
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Udgivet: (2021)

Synthesis and Some Properties of 2-Amino-4-aryl-6-hexyl-7-hydroxy-4H-chromene-3-carbonitriles
af: Dotsenko, V. V., и др.
Udgivet: (2023)

A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities
af: Aksenov, N. A., и др.
Udgivet: (2018)

Synthesis and structure of new 3,7-diazabicyclo[3.3.1]nonane derivatives
af: Dotsenko, V. V., и др.
Udgivet: (2018)

Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives
af: Dotsenko, V. V., и др.
Udgivet: (2019)

Substituted N-(thieno[2,3-b]pyridine-3-yl)acetamides: synthesis, reactions, and biological activity
af: Dotsenko, V. V., и др.
Udgivet: (2019)

Synthesis, structure, and biological activity of 2,6-diazido-4-methylnicotinonitrile derivatives
af: Aksenov, N. A., и др.
Udgivet: (2018)

Aminomethylation of Guareschi imides: synthesis of 2,4-dioxo-1H,5H-3,7-spiro[diazabicyclo[3.3.1]nonane-9,4'-piperidine]-1,5-dicarbonitriles
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Udgivet: (2018)