Direct conversion of 3-(2-nitroethyl)-1H-indoles into 2-(1H-indol-2-yl)acetonitriles

The recently discovered [4+1]-spirocyclization of nitroalkenes to indoles provided a convenient new approach to 2-(1H-indol-2-yl)acetonitriles. However, this reaction was complicated by the formation of inert 3-(2-nitroethyl)-1H-indole byproducts. Herein, we offer a workaround this problem that allo...

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Bibliografiska uppgifter
Huvudupphovsmän:	Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Aleksandrova, E. V., Александрова, Е. В., Aksenov, D. A., Аксенов, Д. А., Grishin, I. Y., Гришин, И. Ю., Rubin, M. A., Рубин, М. А.
Materialtyp:	Статья
Språk:	English
Publicerad:	MDPI 2021
Ämnen:	Nitroalkanes Cascade transformations Heterocycles 1,2-alkyl shift Rearrangements
Länkar:	https://dspace.ncfu.ru/handle/20.500.12258/18235
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https://dspace.ncfu.ru/handle/20.500.12258/18235

Direct conversion of 3-(2-nitroethyl)-1H-indoles into 2-(1H-indol-2-yl)acetonitriles

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