2-Amino-4,5-dihydrothiophene-3-carbonitriles: A New Synthesis, Quantum Chemical Studies, and Mannich-Type Reactions Leading to New Hexahydrothieno[2,3-d]pyrimidines

2-Amino-4,5-dihydrothiophene-3-carbonitriles: A New Synthesis, Quantum Chemical Studies, and Mannich-Type Reactions Leading to New Hexahydrothieno[2,3-d]pyrimidines

trans-2-Amino-4-aryl-5-benzoyl-4,5-dihydrothiophene-3-carbonitriles were prepared either by the reaction of 3-aryl-2-cyanothioacrylamides with α-thiocyanatoacetophenone or by the Michael-type addition of cyanothioacetamide to α-bromochalcones followed by intramolecular cyclization. The mechanism of...

Full beskrivning

Sparad:

Bibliografiska uppgifter
Huvudupphovsmän:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Materialtyp:	Статья
Språk:	English
Publicerad:	American Chemical Society 2021
Ämnen:	2-Amino-4,5-dihydrothiophene-3-carbonitriles Quantum chemical studies Mannich-Type Reactions
Länkar:	https://dspace.ncfu.ru/handle/20.500.12258/18471
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!

Liknande verk

New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
av: Dotsenko, V. V., et al.
Publicerad: (2019)

Crystal structure and properties of new benzimidazopyrido[2,3-b]indole-6-carbonitriles
av: Demidov, O. P., et al.
Publicerad: (2024)

First Synthesis of 2-Amino-5-hydroxy-4H-chromene-3-carbonitriles from 4-(2-Pyridylazo)resorcinol
av: Dotsenko, V. V., et al.
Publicerad: (2023)

7-(2-Aryl-1-cyanovinyl)-1,2,3,4-tetrahydropyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles: Synthesis and Biological Activity
av: Dotsenko, V. V., et al.
Publicerad: (2023)

Synthesis and Some Properties of 2-Amino-4-aryl-6-hexyl-7-hydroxy-4H-chromene-3-carbonitriles
av: Dotsenko, V. V., et al.
Publicerad: (2023)

Some new reactions and properties of xanthane hydride (5-amino-1,2,4-dithiazole-3-thione)
av: Dotsenko, V. V., et al.
Publicerad: (2018)

Mannich Reaction Involving 6-Amino-4-methyl-2-(thio)oxo-1,2-dihydropyridine-3,5-dicarbonitriles
av: Strelkov, V. D., et al.
Publicerad: (2023)

Synthesis and properties of new 4-oxo-4,5-dihydro-1,3-oxazolium perchlorates
av: Dotsenko, V. V., et al.
Publicerad: (2019)

Synthesis of thiazolo[3,2-a]pyridines via an unusual Mannich-type cyclization
av: Dotsenko, V. V., et al.
Publicerad: (2018)

Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
av: Dotsenko, V. V., et al.
Publicerad: (2018)

New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents
av: Dotsenko, V. V., et al.
Publicerad: (2022)

1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction
av: Dotsenko, V. V., et al.
Publicerad: (2021)

Synthesis and Aminomethylation of 6-Amino-2-(dicyanomethylene)-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile Morpholinium Salt
av: Dotsenko, V. V., et al.
Publicerad: (2021)

New Heterocyclization Reactions with Malononitrile Dimer
av: Dotsenko, V. V., et al.
Publicerad: (2024)

Synthesis and structure of new 3,7-diazabicyclo[3.3.1]nonane derivatives
av: Dotsenko, V. V., et al.
Publicerad: (2018)

Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives
av: Dotsenko, V. V., et al.
Publicerad: (2021)

Oxidation of 4,6-Dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitriles with Potassium Ferricyanide: Synthesis and Molecular Docking of Bis(pyrid-2-yl) Disulfides
av: Dotsenko, V. V., et al.
Publicerad: (2024)

Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Hydroxycyclohexanones
av: Dotsenko, V. V., et al.
Publicerad: (2019)

Легкие мелодические этюды для скрипки. Соч. 45 ноты
av: Вольфарт Ф.
Publicerad: (2024)

Synthesis and Cyclizations of N-(Thieno[2,3-b]pyridin-3-yl)cyanoacetamides
av: Dotsenko, V. V., et al.
Publicerad: (2019)

The New Dress
av: Woolf V.
Publicerad: (2013)

Catalyst-free Biginelli-type synthesis of new functionalized 4,7-dihydropyrazolo[1,5-: A] pyrimidines
av: Dotsenko, V. V., et al.
Publicerad: (2018)

Reaction of ethoxymethylenemalonate with cyanothioacetamide in the presence of triethylamine: formation of 1,5-diamino-2,4-dicyano-5-thioxopenta-1,3-diene-1-thiolate and unexpected aminomethylation result
av: Dotsenko, V. V., et al.
Publicerad: (2020)

Oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols, a new approach to the synthesis of benzofuro[3,2-d]pyrimidines
av: Shcherbakov, S. V., et al.
Publicerad: (2023)

N-Hydroxymethylation of 3-Aryl-2-cyanoprop-2-enethioamides
av: Dotsenko, V. V., et al.
Publicerad: (2020)

7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity
av: Dotsenko, V. V., et al.
Publicerad: (2022)

COMPUTER QUANTUM CHEMICAL MODELING OF THE INTERACTION OF CALCIUM PHOSPHATE WITH AMINO ACIDS
av: Blinova, A. A., et al.
Publicerad: (2023)

The New Catacomb
av: Conan D. A.
Publicerad: (2013)

The New Machiavelli
av: Wells, H. G.

The New Magdalen
av: Collins, W.

Synthesis and properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
av: Dotsenko, V. V., et al.
Publicerad: (2019)

A new synthetic approach to functionalized bicyclo[3.2.1]octanes
av: Dotsenko, V. V., et al.
Publicerad: (2018)

New 6'-Amino-5'-cyano-2-oxo-1,2-dihydro-1'H-spiro[indole-3,4'-pyridine]-3'-carboxamides: Synthesis, Reactions, Molecular Docking Studies and Biological Activity
av: Dotsenko, V. V., et al.
Publicerad: (2023)

Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives
av: Dotsenko, V. V., et al.
Publicerad: (2019)

Elsie in New York
av: Henry O.
Publicerad: (2014)

The Child's faith is new
av: Emily E. D.
Publicerad: (2013)

The New Adam and Eve
av: Nathaniel H.
Publicerad: (2014)

The New Vicar of Bray
av: George G. B.
Publicerad: (2013)

Beginning the New Year
av: Bennett E. A.
Publicerad: (2013)

In a New Bottle
av: Bennett E. A.
Publicerad: (2013)