An efficient approach to 2-CF3-indoles based on ortho-nitrobenzaldehydes
The catalytic olefination reaction of 2-nitrobenzaldehydes with CF3 CCl3 afforded stereose-lectively trifluoromethylated ortho-nitrostyrenes in up to 88% yield. The reaction of these alkenes with pyrrolidine permits preparation of α-CF3-β-(2-nitroaryl) enamines. Subsequent one pot reduction of nitro...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Статья |
| Language: | English |
| Published: |
MDPI
2021
|
| Subjects: | |
| Online Access: | https://dspace.ncfu.ru/handle/20.500.12258/18555 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|