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Synthesis, structure, and analgesic activity of 4-(5-Cyano-{4-(fur-2-yl)-1,4-dihydropyridin-3-yl}carboxamido)benzoic acids ethyl esters

A series of new hybrid molecules containing fragments of anestesin and4-(2-furyl)-1,4-dihydronicotinonitrile have been obtained starting fromdiketene, ethyl 4-aminobenzoate, cyanothioacetamide, and furfural. The obtainedcompounds have been investigated for the analgesic activity in vivo (rats) in th...

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Главные авторы: Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Format: Статья
Sprog:English
Udgivet: Pleiades journals 2022
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Online adgang:https://dspace.ncfu.ru/handle/20.500.12258/18606
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