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New Hybrid Molecules Based on Sulfur-Containing Nicotinonitriles: Synthesis, Analgesic Activity in Acetic Acid-Induced Writhing Test, and Molecular Docking Studies

New hybrid molecules bearing furyl and 1,4-dihydronicotinonitrile (or 1,4,5,6-tetrahydronicotinonitrile) fragments have been prepared. The analgesic activity was studied in vivo (rats) in acetic acid-induced writhing test. Some compounds showed activity exceeding that of the reference compound (meta...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Fformat: Статья
Iaith:English
Cyhoeddwyd: Pleiades journals 2022
Pynciau:
Mynediad Ar-lein:https://dspace.ncfu.ru/handle/20.500.12258/21197
Tagiau: Ychwanegu Tag
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