New Hybrid Molecules Based on Sulfur-Containing Nicotinonitriles: Synthesis, Analgesic Activity in Acetic Acid-Induced Writhing Test, and Molecular Docking Studies
New hybrid molecules bearing furyl and 1,4-dihydronicotinonitrile (or 1,4,5,6-tetrahydronicotinonitrile) fragments have been prepared. The analgesic activity was studied in vivo (rats) in acetic acid-induced writhing test. Some compounds showed activity exceeding that of the reference compound (meta...
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| Главные авторы: | , , , , , |
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| Format: | Статья |
| Sprog: | English |
| Udgivet: |
Pleiades journals
2022
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| Fag: | |
| Online adgang: | https://dspace.ncfu.ru/handle/20.500.12258/21197 |
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