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PEG-4000 increases solubility and dissolution rate of vinpocetin in solid dispersion system

In the present work, we determined the optimal ratio of vinpocetine and polyethylene glycol within a solid dispersion (1:2 or 1:5) according to the simulation results in the framework of molecular dynamics associated with the release of the reactant into aqueous medium. For the simulation of vinpoce...

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Bibliographic Details
Main Authors: Glizhova, T. N., Глижова, Т. Н., Arutyunova, N. V., Арутюнова, Н. В., Sokulskaya, N. N., Сокульская, Н. Н.
Format: Статья
Language:English
Published: Ural Federal University 2022
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Online Access:https://dspace.ncfu.ru/handle/20.500.12258/21859
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