Reductive Cleavage of 4′ H-Spiro[indole-3,5′-isoxazoles] en Route to 2-(1 H-Indol-3-yl)acetamides with Anticancer Activities
Unusual cascade transformation involving ring opening and 1,2-alkyl shift was observed upon the reduction of 4′H-spiro[indole-3,5′-isoxazoles] or 2-(3-oxoindolin-2-yl)acetonitriles with sodium borohydride. This reaction allowed for expeditious and highly efficient preparation of 2-(1H-Indol-3-yl)ace...
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
American Chemical Society
2022
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| Темы: | |
| Online-ссылка: | https://dspace.ncfu.ru/handle/20.500.12258/21960 |
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