A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons

A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons

The SARS-CoV-2 delta variant (B.1.617.2) appeared for the first time in December 2020 and later spread worldwide. Currently available vaccines are not so efficacious in curbing the viral pathogenesis of the delta strain of COVID; therefore, the development of a safe and effective vaccine is required...

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Главные авторы:	Rzhepakovsky, I. V., Ржепаковский, И. В.
格式:	Статья
语言:	English
出版:	2023
主题:	SARS-CoV-2 delta vaccine candidate Codon pair Codon context Rare codon Synthetic biology Codon optimization
在线阅读:	https://dspace.ncfu.ru/handle/20.500.12258/23532
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