Synthesis of β-Carbolines with Electrocyclic Cyclization of 3-Nitrovinylindoles

Synthesis of β-Carbolines with Electrocyclic Cyclization of 3-Nitrovinylindoles

The β-carboline motif is common in drug discovery and among numerous biologically active natural products. However, its synthetic preparation relies on multistep sequences and heavily depends on the type of substitution required in the core of the desired β-carboline target. Herein, we demonstrate t...

Kaydedildi:

Detaylı Bibliyografya
Asıl Yazarlar:	Aksenov, N. A., Аксенов, Н. А., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, A. V., Аксенов, А. В., Kirilov, N. K., Кирилов, Н. К., Aksenova, I. V., Аксенова, И. В., Aksenov, D. A., Аксенов, Д. А., Aleksandrova, E. V., Александрова, Е. В., Rubin, M. A., Рубин, М. А.
Materyal Türü:	Статья
Dil:	English
Baskı/Yayın Bilgisi:	2023
Konular:	Beta-carboline Indole Electrocyclization Harmane Heterocycle Norharmane
Online Erişim:	https://dspace.ncfu.ru/handle/20.500.12258/25549
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller

Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2022)

Synthesis of chromenoimidazocarbolines by a reaction of quaternary iminium salts with o-hydroxybenzaldehydes
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Synthesis of chromenoimidazocarbolines by a reaction of quaternary iminium salts with o-hydroxybenzaldehydes
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
Yazar:: Demidov, O. P., ve diğerleri
Baskı/Yayın Bilgisi: (2023)

Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Hydroxycyclohexanones
Yazar:: Dotsenko, V. V., ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Unexpected cyclization ortho-nitrochalcones into 2-alkylideneindolin-3-ones
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2020)

A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2023)

Modeling stages of domino reaction of thiopyrano[4,3-b]indole-3(5H)-thiones and dimethyl acetylenedicarboxylate: a new synthetic route to γ-carbolines with thione group
Yazar:: Demidov, O. P., ve diğerleri
Baskı/Yayın Bilgisi: (2024)

Phytosterols: from preclinical evidence to potential clinical applications
Yazar:: Orobinskaya, V. N., ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Unexpected cyclization of 2-(2-aminophenyl)indoles with nitroalkenes to furnish indolo[3,2-: C] quinolines
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Synthesis of 11H-indolo[3,2-c]quinolines by SnCl4-catalyzed cyclization of indole-3-carbaldehyde oximes
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2020)

Modern trends of organic chemistry in russian universities
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Introduction of tetrazol-1-yl and 5-methyltetrazol-1-yl substituents in the phenyl ring of dibenzo-18-crown-6
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Modern trends of organic chemistry in russian universities
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Oxidative Cyclization of 4-(2-Aminophenyl)-4-oxo-2-phenylbutanenitriles into 2-(3-Oxoindolin-2-ylidene)acetonitriles
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2022)

Synthesis of 2-(1H-Indol-2-yl)acetamides via bronsted acid-assisted cyclization cascade
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2020)

New photochromic indoline spiropyrans containing cationic substituent in the 2H-chromene moiety
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Design, Synthesis, and Screening of Pyridothieno[3,2- b ]indole and Pyridothieno[3,2- c ]cinnoline Derivatives as Potential Biologically Active Molecules
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2022)

Study of the Magnesium Comenate Structure, Its Neuroprotective and Stress-Protective Activity
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2023)

On the structure of zinc(II) coordination compounds with l-histidine
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2020)

Structure and properties of europium (III) triaquatriglycinate chloride
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2020)

Synthesis of 4-(pyrazol-1-yl)pyrimidines from 4-hydrazinopyrimidines and investigation of their structure and some chemical properties
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2024)

Preparation of 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2: H -pyrrol-2-ones via base-assisted cyclization of 3-cyanoketones
Yazar:: Aksenov, N. A., ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Dihydro-2: H -thiopyran-3(4 H)-one-1,1-dioxide-a versatile building block for the synthesis of new thiopyran-based heterocyclic systems
Yazar:: Dotsenko, V. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Domino reactions of 1-substituted N-(cyanomethyl)isoquinolinium salts with salicylic aldehydes
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Reaction of benzyne with 1,2,3,4-tetrahydroisoquinolines as an access to 1H-3-benzazepines
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Reactions of 3,4-dihydroisoquinolines and dihydrothieno[3,2-c]pyridines with benzyne
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Interaction of condensed tetrahydropyrido[4,3-d]pyrimidin-4-ones with dehydrobenzene – synthesis of 6-vinylpyrimidinones fused with five-membered heterocycle containing two or three heteroatoms
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

First synthesis of heterocyclic allenes-benzazecine derivatives
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Three-component reaction of ketals, isonitriles, and trimethylsilyl azide
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

Histological studies of organs in experiment on the application of a niosomal form of anti-tumor medicine
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2020)

The green chemistry paradigm in modern organic synthesis
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2024)

A novel multi-component approach to the synthesis of pyrrolo[2,1-a] isoquinoline derivatives
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2018)

A new series of acetohydroxamates shows in vitro and in vivo anticancer activity against melanoma
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Electrophilically activated nitroalkanes in double annulation of [1,2,4]triazolo[4,3-a]quinolines and 1,3,4-oxadiazole rings
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2021)

Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives
Yazar:: Aksenov, A. V., ve diğerleri
Baskı/Yayın Bilgisi: (2022)