Targeted Synthesis of New 5-Phenyl-2-[(E)-Styryl]-1H-Pyrimidin-6-One Derivatives and Their Inhibitory Activity Toward SARS-CoV-2 Major (MPRO) and Papain-Like Proteases (PLPRO)
The use of the 5-phenyl-1H-pyrimidin-6-one scaffold in the search for biologically active compounds with antiviral activity based on the pyrimidin-4-one core present in endogenous substances and drugs was substantiated. The molecular activity and pharmacokinetic descriptors for styryl derivatives of...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Статья |
| Langue: | English |
| Publié: |
2024
|
| Sujets: | |
| Accès en ligne: | https://dspace.ncfu.ru/handle/20.500.12258/26581 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|