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One-step synthesis of 4-methyl-2-substituted quinazoline-3-oxides via polyphosphoric acid catalyzed acylation of electron-rich anilides with nitroethane

One-step synthesis of 4-methyl-2-substituted quinazoline-3-oxides via polyphosphoric acid catalyzed acylation of electron-rich anilides with nitroethane

A diverse set of 4-methyl-2-substituted quinazoline-3-oxides has been prepared using polyphosphoric acid both as a reaction medium and a Brønsted-acid catalyst. The reaction proceeds in a domino fashion via the formation of a corresponding oxime followed by exo-trig cyclization and elimination of a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grishin, I. Y., Гришин, И. Ю., Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Leontiev, A. V., Леонтьев, А. В., Aksenov, D. A., Аксенов, Д. А.
Fformat: Статья
Iaith:English
Cyhoeddwyd: 2024
Pynciau:
Nitroalkanes
Quinozalines
Acylamination
Cascade transformations
Heterocyclic compounds
N-oxides
Polyphosphoric acid
Mynediad Ar-lein:https://dspace.ncfu.ru/handle/20.500.12258/26766
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https://dspace.ncfu.ru/handle/20.500.12258/26766

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