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Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas

Direct and facile synthesis of 9-aminoacridine and acridin-9-yl-ureas

The ability of urea anions to react as nucleophiles with acridine has been investigated. An effective SNH synthesis of 9-aminoacridine was developed using the urea/NaH/DMSO system. However, when mono substituted ureas containing bulky substituents or 1,1-dialkyl substituted ureas were used, products...

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Главные авторы: Borovlev, I. V., Боровлев, И. В., Demidov, O. P., Демидов, О. П., Amangasieva, G. A., Амангазиева, Г. А., Avakyan, E. K., Авакян, Е. К.
格式: Статья
語言:English
出版: Elsevier Ltd 2018
主題:
Facile synthesis
Direct synthesis
9-aminoacridine
Acridin-9-yl-ureas
在線閱讀:https://www.scopus.com/record/display.uri?eid=2-s2.0-84978224689&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=94a185ef2a894025076dc32df599dd02&sot=afnl&sdt=cl&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=89&citeCnt=4&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3330
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https://www.scopus.com/record/display.uri?eid=2-s2.0-84978224689&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=94a185ef2a894025076dc32df599dd02&sot=afnl&sdt=cl&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=89&citeCnt=4&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3330

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