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Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides

Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides

A highly efficient one-pot method for the reductive coupling of indoles to nitrostyrenes in polyphosphoric acid doped with PCl3 was developed. This method allows direct and expeditious access to primary (indol-3-yl)acetamides, interesting as anti-cancer drug candidates

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Príomhchruthaitheoirí: Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Dzhandigova, Z. V., Джандигова, З. В., Aksenov, D. A., Аксенов, Д. А., Rubin, M. A., Рубин, М. А.
Formáid: Статья
Teanga:English
Foilsithe / Cruthaithe: Royal Society of Chemistry 2018
Ábhair:
Anticancer drug
En-route
One-pot method
Polyphosphoric acids
Reductive couplings
Rochtain ar líne:https://dspace.ncfu.ru/handle/20.500.12258/3436
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https://dspace.ncfu.ru/handle/20.500.12258/3436

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