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Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides

A highly efficient one-pot method for the reductive coupling of indoles to nitrostyrenes in polyphosphoric acid doped with PCl3 was developed. This method allows direct and expeditious access to primary (indol-3-yl)acetamides, interesting as anti-cancer drug candidates

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Главные авторы: Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Dzhandigova, Z. V., Джандигова, З. В., Aksenov, D. A., Аксенов, Д. А., Rubin, M. A., Рубин, М. А.
Формат: Статья
Язык:English
Опубликовано: Royal Society of Chemistry 2018
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Online-ссылка:https://dspace.ncfu.ru/handle/20.500.12258/3436
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spelling ir-20.500.12258-34362025-02-13T12:34:48Z Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides Aksenov, A. V. Аксенов, А. В. Aksenov, N. A. Аксенов, Н. А. Dzhandigova, Z. V. Джандигова, З. В. Aksenov, D. A. Аксенов, Д. А. Rubin, M. A. Рубин, М. А. Anticancer drug En-route One-pot method Polyphosphoric acids Reductive couplings A highly efficient one-pot method for the reductive coupling of indoles to nitrostyrenes in polyphosphoric acid doped with PCl3 was developed. This method allows direct and expeditious access to primary (indol-3-yl)acetamides, interesting as anti-cancer drug candidates 2018-11-16T13:14:18Z 2018-11-16T13:14:18Z 2016 Статья Aksenov, A.V., Aksenov, N.A., Dzhandigova, Z.V., Aksenov, D.A., Voskressensky, L.G., Nenajdenko, V.G., Rubin, M. Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides // RSC Advances. - 2016. - Volume 6. - 2016. - Issue 96. - Pages 93881-93886 http://hdl.handle.net/20.500.12258/3436 en RSC Advances application/pdf application/pdf Royal Society of Chemistry
institution СКФУ
collection Репозиторий
language English
topic Anticancer drug
En-route
One-pot method
Polyphosphoric acids
Reductive couplings
spellingShingle Anticancer drug
En-route
One-pot method
Polyphosphoric acids
Reductive couplings
Aksenov, A. V.
Аксенов, А. В.
Aksenov, N. A.
Аксенов, Н. А.
Dzhandigova, Z. V.
Джандигова, З. В.
Aksenov, D. A.
Аксенов, Д. А.
Rubin, M. A.
Рубин, М. А.
Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
description A highly efficient one-pot method for the reductive coupling of indoles to nitrostyrenes in polyphosphoric acid doped with PCl3 was developed. This method allows direct and expeditious access to primary (indol-3-yl)acetamides, interesting as anti-cancer drug candidates
format Статья
author Aksenov, A. V.
Аксенов, А. В.
Aksenov, N. A.
Аксенов, Н. А.
Dzhandigova, Z. V.
Джандигова, З. В.
Aksenov, D. A.
Аксенов, Д. А.
Rubin, M. A.
Рубин, М. А.
author_facet Aksenov, A. V.
Аксенов, А. В.
Aksenov, N. A.
Аксенов, Н. А.
Dzhandigova, Z. V.
Джандигова, З. В.
Aksenov, D. A.
Аксенов, Д. А.
Rubin, M. A.
Рубин, М. А.
author_sort Aksenov, A. V.
title Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
title_short Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
title_full Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
title_fullStr Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
title_full_unstemmed Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
title_sort direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
publisher Royal Society of Chemistry
publishDate 2018
url https://dspace.ncfu.ru/handle/20.500.12258/3436
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