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Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides

Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides

A highly efficient one-pot method for the reductive coupling of indoles to nitrostyrenes in polyphosphoric acid doped with PCl3 was developed. This method allows direct and expeditious access to primary (indol-3-yl)acetamides, interesting as anti-cancer drug candidates

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Bibliographic Details
Main Authors: Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Dzhandigova, Z. V., Джандигова, З. В., Aksenov, D. A., Аксенов, Д. А., Rubin, M. A., Рубин, М. А.
Format: Статья
Language:English
Published: Royal Society of Chemistry 2018
Subjects:
Anticancer drug
En-route
One-pot method
Polyphosphoric acids
Reductive couplings
Online Access:https://www.scopus.com/record/display.uri?eid=2-s2.0-84991336276&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=f2513aeb9baa9b141865ee13207ae43d&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Direct+reductive+coupling+of+indoles+to+nitrostyrenes+en+route+to%29&relpos=0&citeCnt=1&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3436
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https://www.scopus.com/record/display.uri?eid=2-s2.0-84991336276&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=f2513aeb9baa9b141865ee13207ae43d&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Direct+reductive+coupling+of+indoles+to+nitrostyrenes+en+route+to%29&relpos=0&citeCnt=1&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3436

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