コンテンツを見る
Metal-templated assembly of cyclopropane-fused diazepanones and diazecanones via exo- trig nucleophilic cyclization of cyclopropenes with tethered carbamates

Metal-templated assembly of cyclopropane-fused diazepanones and diazecanones via exo- trig nucleophilic cyclization of cyclopropenes with tethered carbamates

A strain-release-driven, cation-templated nucleophilic 7- and 8-exo-trig-cyclization of tethered Boc-protected amines to cyclopropenes is described. The featured reaction proceeds in diastereo- and regioselective fashion and allows for preparation of the corresponding 2,5-diazabicyclo[5.1.0]octan-6-...

詳細記述

保存先:
書誌詳細
主要な著者: Rubin, M. A., Рубин, М. А.
フォーマット: Статья
言語:English
出版事項: American Chemical Society 2018
主題:
Metal-Templated Assembly
Nucleophilic Cyclization
Tethered Carbamates
オンライン･アクセス:https://www.scopus.com/record/display.uri?eid=2-s2.0-85056148282&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=6bb4e38e48c5091ac82975132bd42355&sot=afnl&sdt=sisr&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Metal-Templated+Assembly+of+Cyclopropane-Fused+Diazepanones+and+Diazecanones+via+exo-+trig+Nucleophilic+Cyclization+of+Cyclopropenes+with+Tethered+Carbamates%29&relpos=0&citeCnt=0&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3445
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
その他の書誌記述
要約:A strain-release-driven, cation-templated nucleophilic 7- and 8-exo-trig-cyclization of tethered Boc-protected amines to cyclopropenes is described. The featured reaction proceeds in diastereo- and regioselective fashion and allows for preparation of the corresponding 2,5-diazabicyclo[5.1.0]octan-6-ones and 2,6-diazabicyclo[6.1.0]nonan-7-ones as sole products in high yields. Preliminary studies on anticancer activities of these novel cyclopropane-fused medium heterocycles were performed

類似資料