Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives
2,4-Dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile reacted with primary amines and formaldehyde on heating in boiling ethanol to give mixtures of 7-alkyl-2,4-dioxo-3,7-diazaspiro[bicyclo[3.3.1]nonane- 9,1-cyclohexane]-1,5-dicarbonitriles and their ammonium salts. The former were isolated in 26-71%...
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| Autori principali: | , , , , , |
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| Natura: | Статья |
| Lingua: | English |
| Pubblicazione: |
MAIK NAUKA/INTERPERIODICA/SPRINGER
2019
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| Accesso online: | http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=48&SID=C3mo2Vj4mODIAgwCW4S&page=1&doc=1 https://dspace.ncfu.ru/handle/20.500.12258/5056 |
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