Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives
2,4-Dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile reacted with primary amines and formaldehyde on heating in boiling ethanol to give mixtures of 7-alkyl-2,4-dioxo-3,7-diazaspiro[bicyclo[3.3.1]nonane- 9,1-cyclohexane]-1,5-dicarbonitriles and their ammonium salts. The former were isolated in 26-71%...
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2019
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ir-20.500.12258-50562025-02-13T09:38:20Z Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. 2,4-Dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile reacted with primary amines and formaldehyde on heating in boiling ethanol to give mixtures of 7-alkyl-2,4-dioxo-3,7-diazaspiro[bicyclo[3.3.1]nonane- 9,1-cyclohexane]-1,5-dicarbonitriles and their ammonium salts. The former were isolated in 26-71% after acidification of the reaction mixture 2019-03-22T14:25:54Z 2019-03-22T14:25:54Z 2018 Статья Khrustaleva, AN; Frolov, KA; Dotsenko, VV; Aksenov, NA; Aksenova, IV; Krivokolysko, BS; Krivokolysko, SG. Aminomethylation of 2,4-Dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient Synthesis of New 3,7-Diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] Derivatives // RUSSIAN JOURNAL OF ORGANIC CHEMISTRY. - 2018. -Том: 54. - Выпуск: 12. - Стр.: 1803-1806 http://hdl.handle.net/20.500.12258/5056 en Russian Journal of Organic Chemistry application/pdf application/pdf MAIK NAUKA/INTERPERIODICA/SPRINGER |
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СКФУ |
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Репозиторий |
| language |
English |
| description |
2,4-Dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile reacted with primary amines and formaldehyde on heating in boiling ethanol to give mixtures of 7-alkyl-2,4-dioxo-3,7-diazaspiro[bicyclo[3.3.1]nonane- 9,1-cyclohexane]-1,5-dicarbonitriles and their ammonium salts. The former were isolated in 26-71% after acidification of the reaction mixture |
| format |
Статья |
| author |
Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. |
| spellingShingle |
Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| author_facet |
Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. |
| author_sort |
Dotsenko, V. V. |
| title |
Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| title_short |
Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| title_full |
Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| title_fullStr |
Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| title_full_unstemmed |
Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| title_sort |
aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives |
| publisher |
MAIK NAUKA/INTERPERIODICA/SPRINGER |
| publishDate |
2019 |
| url |
https://dspace.ncfu.ru/handle/20.500.12258/5056 |
| work_keys_str_mv |
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