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Aminomethylation of 2,4-dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile. Efficient synthesis of new 3,7-diazaspiro- [bicyclo[3.3.1]nonane-9,1-cyclohexane] derivatives

2,4-Dioxo-3-azaspiro[5.5]undecane-1,5-dicarbonitrile reacted with primary amines and formaldehyde on heating in boiling ethanol to give mixtures of 7-alkyl-2,4-dioxo-3,7-diazaspiro[bicyclo[3.3.1]nonane- 9,1-cyclohexane]-1,5-dicarbonitriles and their ammonium salts. The former were isolated in 26-71%...

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Главные авторы: Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
格式: Статья
语言:English
出版: MAIK NAUKA/INTERPERIODICA/SPRINGER 2019
在线阅读:http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=48&SID=C3mo2Vj4mODIAgwCW4S&page=1&doc=1
https://dspace.ncfu.ru/handle/20.500.12258/5056
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