N-substituted 1H-pyrimidin-4-one derivatives possessing anxiolytic activity
The logical framework approach was implemented for designing CNS-active N-substituted 1H-pyrimidin-4-ones. Formation energies of possible ligand—receptor complexes with D2-dopamine and GABAA Receptors were determined from molecular docking calculations. The results allowed the probability of psychot...
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| פורמט: | Статья |
| שפה: | English |
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Springer New York LLC
2018
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| גישה מקוונת: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85029121020&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=nort*+caucas*+fed*+univ*&sid=1946c417b781d61d9cf2ec314093a48c&sot=afnl&sdt=cl&cluster=scopubyr%2c%222017%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=37&citeCnt=0&searchTerm= https://dspace.ncfu.ru:443/handle/20.500.12258/692 |
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https://www.scopus.com/record/display.uri?eid=2-s2.0-85029121020&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=nort*+caucas*+fed*+univ*&sid=1946c417b781d61d9cf2ec314093a48c&sot=afnl&sdt=cl&cluster=scopubyr%2c%222017%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=37&citeCnt=0&searchTerm=https://dspace.ncfu.ru:443/handle/20.500.12258/692