Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives

Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives

Cyanothioacetamide reacted with 1,1,5,5-tetrafluoroacetylacetone to give 4,6-bis(difluoromethyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile, and alkylation of the latter with α-chloroacetamides afforded 3-amino-4,6-bis(difluoromethyl)thieno[2,3-b]pyridine-2-carboxamides. The structure of the key co...

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Главные авторы:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
格式:	Статья
语言:	English
出版:	Pleiades Publishing 2019
主题:	Cyanothioacetamide Guareschi-Thorpe reaction In silico biological activity Organic fluorides Thieno[2,3-b]pyridines Thorpe-Ziegler cyclization
在线阅读:	https://www.scopus.com/record/display.uri?eid=2-s2.0-85074090800&origin=resultslist&sort=plf-f&src=s&st1=Synthesis+and+Properties+of+New+Fluorine-Containing+Thieno%5b2%2c3-b%5dpyridine+Derivatives&st2=&sid=4cfb0cd8aa274b454820cc90ab35e786&sot=b&sdt=b&sl=100&s=TITLE-ABS-KEY%28Synthesis+and+Properties+of+New+Fluorine-Containing+Thieno%5b2%2c3-b%5dpyridine+Derivatives%29&relpos=0&citeCnt=0&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/8307
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